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  • Marijuana not Associated w. Psychotic Symptoms in Offspring

    Posted by Spinoza on 2009-10-22 at 16:32

    Maternal Tobacco and Alcohol Use, But Not Marijuana, Associated with Psychotic Symptoms in Offspring, Study Says.

    http://health.usnews.com/articles/health/healthday/2009/10/01/smoking-in-pregnancy-linked-to-psychotic-symptoms.html

    Quote:
    The researchers found that the children whose mothers smoked during pregnancy were more likely to have the symptoms, and the risk rose in those whose mothers smoked the most while pregnant.

    Maternal alcohol use was also linked to more psychotic symptoms in children, but only among those whose mothers drank more than 21 units of alcohol a week during the early weeks of pregnancy (with one unit being roughly equivalent to a half-pint of beer or a glass of wine). The researchers couldn’t find any link between maternal marijuana use and psychotic symptoms in children among the few women who reported using the drug during pregnancy.

    http://bjp.rcpsych.org/cgi/content/full/195/4/294

    Quote:
    Frequency of maternal tobacco use during pregnancy was associated with increased risk of suspected or definite psychotic symptoms (adjusted odds ratio 1.20, 95% CI 1.05–1.37, P = 0.007). Maternal alcohol use showed a non-linear association with psychotic symptoms, with this effect almost exclusively in the offspring of women drinking >21 units weekly. Maternal cannabis use was not associated with psychotic symptoms. Results for paternal smoking during pregnancy and maternal smoking post-pregnancy lend some support for a causal effect of tobacco exposure in utero on development of psychotic experiences.
    replied 13 years ago 1 Member · 1 Reply
  • 1 Reply
  • error

    Member
    2009-10-22 at 23:30

    Summa kardemumma: Kvinnor ska inte dricka under graviditeten, speciellt inte i början av den. Rökning dör man av och dessutom skader det barnet och marijuana är inte så skadligt som alla ovetenskapliga källor påstår.

    Intressant artikel som jag tycker kan påvisa möjlig associationer men man ska dock akta sig för att dra för starka konklusioner och vara öppen för “confounding factors”. Kan se att de försökt eliminera dessa faktorer men är dock skeptisk vid utformningen av denna typ av undersökningar. Tex: Hur mycket ljuger folk om sitt alkohol och tobak missbruk respektive bruk? Fint att det redovisas säkerhetsintervall och P-värde – det kan säga mycket. Artikeln får dock inte så hög evidens på grund av undersöknigens design – fler stora (förhoppningsvis randomiserade, kontrollerade) försök borde utföras för att slutligen konkludera något.